TMED1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Nuclear factor of activated T-cells

Nuclear factor of activated T-cells cytoplasmic 4 is part of a DNA-binding transcription complex

Alternative splicing of this gene produces multiple transcript variants| some encoding different isoforms

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

TMED1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Nuclear factor of activated T-cellsThis gene belongs to the TMED (transmembrane emp24 domain containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene.