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Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging This receptor is activated by

SKU: 75154160860

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Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging This receptor is activated byThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL)

Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome

and inhibiting its expression partially suppresses p53-induced apoptosis

Splice variants have been found for this gene

Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging This receptor is activated byThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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