NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Translocations with the ETV6 gene

Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia

The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors

Activity of this protein is key in the development of neural tissues| particularly the eye

Pseudogenes of this gene have been defined on chromosomes 14 and 17

NFκB-p65(Phospho Ser281) Polyclonal Antibody, 50ul Peptide Library Translocations with the ETV6 geneNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four