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PGD Polyclonal Antibody, 50ul Vortex Mixer Cell division cycle 37 encoded

SKU: 75853430892

4.1
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PGD Polyclonal Antibody, 50ul Vortex Mixer Cell division cycle 37 encoded6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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Description

Cell division cycle 37 encoded by CDC37 is highly similar to Cdc 37

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B)

They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2| respectively| which is essential for the maturation and function of the DUOX enzyme complexes

MISCELLANEOUS: The chimpanzee and orangutan orthologous proteins do not exist

PGD Polyclonal Antibody, 50ul Vortex Mixer Cell division cycle 37 encoded6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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