EDG-4 Polyclonal Antibody, 100ul[BT-AP02829] Metabolic enzymes The encoded protein can bind

The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex

This transport may be important for activation of tyrosine kinases

The encoded protein is thought to have a potential role in the induced radioresistance

The encoded protein interacts with specifc DNA structures including nicked Holliday junctions

EDG-4 Polyclonal Antibody, 100ul[BT-AP02829] Metabolic enzymes The encoded protein can bindLPAR2 (lysophosphatidic acid receptor 2) encodes a member of family I of the G protein coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined.