CLSPN Polyclonal Antibody, 100ul Culture Plate Inserts The N-terminus is poorly conserved

The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family

The encoded protein may play a critical role in the regulation of apoptosis

SLC8 subfamily

This protein and its receptor are both found to be important for B cell development

CLSPN Polyclonal Antibody, 100ul Culture Plate Inserts The N-terminus is poorly conservedThe product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.