IL-5 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) A duplication of LMNB1 is

A duplication of LMNB1 is associated with autosomal dominant adult-onset leukodystrophy (ADLD)

Pseudogenes of this gene are present on chromosomes 1| 3| 9| 12 and 20| and on the X chromosome

This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20

Related pseudogenes have been identified on chromosomes 1 and 14

IL-5 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) A duplication of LMNB1 isIL5 encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. Interleukin 5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the