NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library the short isoform(14 kDa) has
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NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library the short isoform(14 kDa) hasThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments
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