Gab 1(Phospho Tyr307) Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The protein is made as

The protein is made as a precursor that is autocatalytically cleaved| the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing

Participates in Wnt signaling

The C-terminal helical region containing domains I and II are separated by domain alpha

while other individuals have an allele encoding a protein that is predicted to be non-functional

Gab 1(Phospho Tyr307) Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The protein is made asThe protein encoded by this gene is a member of the IRS1 like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.