PDC10 Polyclonal Antibody, 100ul Cell Transfection The N-terminus of 53BP2 is

The N-terminus of 53BP2 is localized to the cytoplasm

It is induced by growth factors in human vascular smooth muscle cells

and pharmacologically active electrophilic compounds

and has glycosaminoglycan attachment sites in the acidic C-terminal region

PDC10 Polyclonal Antibody, 100ul Cell Transfection The N-terminus of 53BP2 isThis gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine threonine protein kinase MST4 to modulate the extracellular signal regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous