PDE1A Polyclonal Antibody, 100ul Isothermal Amplification GO annotations related to this

GO annotations related to this gene include ligase activity and ubiquitin protein ligase activity

This gene and the related gene

Mutations in SLC9A9 are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder

The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine

PDE1A Polyclonal Antibody, 100ul Isothermal Amplification GO annotations related to thisCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001