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ApoA-IV Monoclonal Antibody, 100ul[BT-MCA0166] Transporters Overexpression of some isoforms of

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ApoA-IV Monoclonal Antibody, 100ul[BT-MCA0166] Transporters Overexpression of some isoforms ofApoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396 residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A IV is a potent activator of lecithin cholesterol

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Description

Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression

the protein encoded by MMP14 is a member of the membrane-type MMP (MT-MMP) subfamily

the mature protein downregulates fibrinolysis

Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA

ApoA-IV Monoclonal Antibody, 100ul[BT-MCA0166] Transporters Overexpression of some isoforms ofApoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396 residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A IV is a potent activator of lecithin cholesterol

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