Rb(Phospho Thr821) Polyclonal Antibody, 50ul Bottles This protein binds both the

This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin| and it appears to play a role in calcium homeostasis in the ER

This nuclear enzyme is involved in processes such as chromosome condensation

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Rb(Phospho Thr821) Polyclonal Antibody, 50ul Bottles This protein binds both theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.