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Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domain
Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domain
Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domain
Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domain

Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domain

SKU: 81557699853

4.8
USD123.75 USD153.75

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Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domainApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

tramtrack and bric-a-brac) domain

Additional splice variants of this gene have been described but currently lack transcript support

is expressed primarily in the brain

Mutations in this gene result in Dystonia 3

Ref-1 (Acetyl Lys6) Polyclonal Antibody, 100ul ssDNA Synthesis tramtrack and bric-a-brac) domainApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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