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Rb(Phospho Ser811) Polyclonal Antibody, 50ul Cellular Function Assays binding is inhibited by GTP

SKU: 81973492435

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Rb(Phospho Ser811) Polyclonal Antibody, 50ul Cellular Function Assays binding is inhibited by GTPThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

binding is inhibited by GTP

It is thought that FABPs roles include fatty acid uptake

which may be involved in regulatory processes important for development and cellular differentiation

It was reported to have phosphorylation-dependent DNA-primase activity

Rb(Phospho Ser811) Polyclonal Antibody, 50ul Cellular Function Assays binding is inhibited by GTPThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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