Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments This cyclin and its kinase

This cyclin and its kinase partner are components of TFIIH

May function in transmigration of leukocytes through epithelial and endothelial tissues

and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains

Mutations in SYN1 may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome

Rb(Phospho Thr821) Polyclonal Antibody, 20ul DNA Fragments This cyclin and its kinaseThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.