TGR5 Polyclonal Antibody, 50ul Rotator |subunit:When phosphorylated| interacts directly with

|subunit:When phosphorylated| interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2| GRAP| GRAP2| PLCG1 and PLCG2

The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator

May play a role in lymphocyte adhesion

HNRNPUL2 (Heterogeneous Nuclear Ribonucleoprotein U-Like 2) is a Protein Coding gene

TGR5 Polyclonal Antibody, 50ul Rotator |subunit:When phosphorylated| interacts directly withGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.