eIF4G Polyclonal Antibody, 100ul Metabolic enzymes a gene whose translocation may

a gene whose translocation may be associated with B-cell malignancies

While the long isoform (22 kDa) acts as an activator| the short isoform (14 kDa) has been shown to repress gamma-globin gene expression

73 and 74 have been tested and found to be biologically active

The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis

eIF4G Polyclonal Antibody, 100ul Metabolic enzymes a gene whose translocation mayThe eukaryotic translation initiation factor 4 gamma 1 encoded by EIF4G1 is a component of the multi subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP dependent unwinding of 5' terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a