BID Polyclonal Antibody, 50ul[BT-AP00897] Apoptosis & Autophagy Mutations in this gene have

Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis

and angiogenesis

The encoded protein contains an N-terminal actin-binding domain

BID Polyclonal Antibody, 50ul[BT-AP00897] Apoptosis & Autophagy Mutations in this gene haveBID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. BH3 interacting domain death agonist is a member of the BCL 2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase 8 (CASP8); CASP8 cleaves BH3 interacting domain death agonist, and the COOH terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript