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SLIK4 Polyclonal Antibody, 20ul Serum & Sample Tubes Binds multiple DNA elements such

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SLIK4 Polyclonal Antibody, 20ul Serum & Sample Tubes Binds multiple DNA elements suchThis gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N terminal leucine rich repeat domains similar to those found in the axonal growth controlling protein SLIT, as well as C terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript

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Description

Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer

and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors

A pseudogene of this gene is found on chromosome 13

This gene is found in a cluster with other desmoglein family members on chromosome 18

SLIK4 Polyclonal Antibody, 20ul Serum & Sample Tubes Binds multiple DNA elements suchThis gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N terminal leucine rich repeat domains similar to those found in the axonal growth controlling protein SLIT, as well as C terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript

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