DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 100ul Custom Peptide Synthesis It may play a role

It may play a role in signal transduction cascades in terminally differentiated cells

Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders

The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5

it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production

DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 100ul Custom Peptide Synthesis It may play a roleThe protein encoded by this gene is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4