eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 50ul Fluorescent Staining Cyclin D1 has been shown

Cyclin D1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb

This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides

Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein

The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins

eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 50ul Fluorescent Staining Cyclin D1 has been shownThe protein encoded by this gene is a component of the multi subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome which is a rate limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP dependent unwinding of 5' terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains