CacyBP Polyclonal Antibody, 50ul Peptide Modification Mutation or amplification of REL

Mutation or amplification of REL is associated with B-cell lymphomas

Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis

where it regulates integrin-mediated signal transduction

ZKSCAN5 encodes a zinc finger protein of the Kruppel family

CacyBP Polyclonal Antibody, 50ul Peptide Modification Mutation or amplification of RELCalcyclin binding protein encoded by CACYBP is a calcyclin binding protein. It may be involved in calcium dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin mediated degradation of beta catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.