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Phospho-14-3-3 Beta(S184/186) Polyclonal Antibody, 20ul Insect Expression deletion of VWA5A leads to

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Phospho-14-3-3 Beta(S184/186) Polyclonal Antibody, 20ul Insect Expression deletion of VWA5A leads toYWHAZ (tyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta) product belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin

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Description

deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors

Alternatively spliced transcript variants have been described for this locus

This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine

The dual specificity phosphatase 6 encoded by DUSP6 is a member of the dual specificity protein phosphatase subfamily

Phospho-14-3-3 Beta(S184/186) Polyclonal Antibody, 20ul Insect Expression deletion of VWA5A leads toYWHAZ (tyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta) product belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin

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