MLL4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) In the testis| this protein

In the testis| this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa

Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin

Mutations in this gene are associated with Cenani-Lenz syndrome

a combination of purified CARL-2 for capture and biotinylated CARL-1 for detection is recommended

MLL4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) In the testis| this proteinThis gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C terminal domain that characterizes proteins of the MLL (mixed lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be