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PABP2 Polyclonal Antibody, 100ul Thermal Control and is phosphorylated in response

SKU: 86375744985

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PABP2 Polyclonal Antibody, 100ul Thermal Control and is phosphorylated in responseThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG

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Description

and is phosphorylated in response to cytokine stimulation

The C-terminal half of this protein has been shown to bind DNA

STX3A and STX4A

Alternative splicing results in two transcript variants

PABP2 Polyclonal Antibody, 100ul Thermal Control and is phosphorylated in responseThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG

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