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PKR(Phospho Thr446) Polyclonal Antibody, 100ul Molecular Weight Markers Pseudogenes of this gene are

SKU: 86712347053

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SEK123.75 SEK164.75

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PKR(Phospho Thr446) Polyclonal Antibody, 100ul Molecular Weight Markers Pseudogenes of this gene areThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20

Alternative splicing results in multiple transcript variations

phosphorylation and polyubiquitination

This gene product

PKR(Phospho Thr446) Polyclonal Antibody, 100ul Molecular Weight Markers Pseudogenes of this gene areThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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