PKD1 Polyclonal Antibody, 50ul[BT-AP13117] Antibodies C-mannosylation in the Cys-rich subdomains

C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis

This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region

The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs

which regulates sister chromatid cohesion and recombination between homologous chromosomes

PKD1 Polyclonal Antibody, 50ul[BT-AP13117] Antibodies C-mannosylation in the Cys-rich subdomainsPRKD1 is a serine threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009