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Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing |The glycine-rich region (GRR) appears

SKU: 87252243449

4.3
SEK185.00 SEK210.00

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Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing |The glycine-rich region (GRR) appearsThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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Description

|The glycine-rich region (GRR) appears to be a critical element in the generation of p52

secondary structure can deter the protective function of this protein

Based on studies in chicken and mouse

and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4

Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing |The glycine-rich region (GRR) appearsThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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