WWOX Polyclonal Antibody, 50ul Recombinant Ab Production a large family of receptors

a large family of receptors that have a similar structure characterized by 7 transmembrane domains

it is an acidic protein which heterodimerizes with type II keratins to form hair and nails

and are clustered together on chromosome X

observation and manipulationof samples during collection and storage

WWOX Polyclonal Antibody, 50ul Recombinant Ab Production a large family of receptorsWWOX (WW domain containing oxidoreductase) encodes a member of the short chain dehydrogenases reductases (SDR) protein family. WWOX spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of WWOX is also associated with autosomal recessive spinocerebellar ataxia