UHRF1 Polyclonal Antibody, 100ul Filtration elegans protein that functions in

elegans protein that functions in phagocytosis of apoptotic cells and in cell migration

and participates in suppressing anti-inflammatory responses and insulin sensitizing

Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome

Also detected at high levels in lung carcinoma

UHRF1 Polyclonal Antibody, 100ul Filtration elegans protein that functions inUHRF1 encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. E3 ubiquitin protein ligase UHRF1binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent