TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation Imprinting defects at chromosome 11p13

Imprinting defects at chromosome 11p13 may contribute to tumorigenesis

follicle-stimulating hormone induces egg and sperm production

Charcot-Marie-Tooth disease

It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation Imprinting defects at chromosome 11p13Catalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only