C1INH Polyclonal Antibody, 100ul Lysosome Studies using SLP-76 deficient T

Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function

This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis

Binds to and may be involved in the transforming capacity of the adenovirus E1A protein

tissue specificity:Testis specific

C1INH Polyclonal Antibody, 100ul Lysosome Studies using SLP-76 deficient TSERPING1encodes a highly glycosylated plasma protein (serpin family G member 1)involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.