ATG5 mouse Monoclonal Antibody(8B4), 100ul Fluorescent Staining Mutations in this gene are

Mutations in this gene are associated with osteoarthritis in humans

With its included A8-2 and A4-PCR8 rotors and SA02P2 & SA05P2 adapters

The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1)

Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer

ATG5 mouse Monoclonal Antibody(8B4), 100ul Fluorescent Staining Mutations in this gene areThe protein encoded by this gene, in combination with autophagy protein 12, functions as an E1 like activating enzyme in a ubiquitin like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation,