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OLIG2 Rabbit Polyclonal Antibody, 50ul Fluorescent Staining The protein encoded by ARNTL

SKU: 94574635650

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SEK162.00 SEK193.00

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OLIG2 Rabbit Polyclonal Antibody, 50ul Fluorescent Staining The protein encoded by ARNTLThis gene encodes a basic helix loop helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14; 21)(q11. 2; q22) associated with T cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning

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Description

The protein encoded by ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK

The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK

Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets

The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes

OLIG2 Rabbit Polyclonal Antibody, 50ul Fluorescent Staining The protein encoded by ARNTLThis gene encodes a basic helix loop helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14; 21)(q11. 2; q22) associated with T cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning

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