HNF-4 alpha/ gamma (Acetyl Lys127/79) Polyclonal Antibody, 100ul Pipette Filler Alternate splicing of CREB1 results

Alternate splicing of CREB1 results in several transcript variants encoding different isoforms

Seems to play a role in p53-mediated apoptosis induction

which was up-regulated in antigen immunization induced germinal center

Dok-3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B cells and macrophages

HNF-4 alpha/ gamma (Acetyl Lys127/79) Polyclonal Antibody, 100ul Pipette Filler Alternate splicing of CREB1 resultsThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin