OAT Polyclonal Antibody, 100ul DNA Fragments Defects in this gene cause

Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)

promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells

FAM48A is required for MAP kinase p38 activation during gastrulation and for starvation-induced ATG9A trafficking during autophagy

Among its related pathways are mRNA Splicing - Major Pathway

OAT Polyclonal Antibody, 100ul DNA Fragments Defects in this gene causeOAT encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been