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MYO3B Polyclonal Antibody, 50ul Mini dry bath The human HUNK gene localizes

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MYO3B Polyclonal Antibody, 50ul Mini dry bath The human HUNK gene localizesThis gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production

subcellular location:Also present in PML nuclear bodies

MYO3B Polyclonal Antibody, 50ul Mini dry bath The human HUNK gene localizesThis gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms.

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