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CD327 Polyclonal Antibody, 50ul Peptide Synthesis Different mutations in the mouse

SKU: 9625702454

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CD327 Polyclonal Antibody, 50ul Peptide Synthesis Different mutations in the mouseThis gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin like lectin) family of proteins. The encoded transmembrane receptor binds sialyl TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.

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Description

Different mutations in the mouse homologs| En1 and En2| produced different developmental defects that frequently are lethal

This protein forms a kinase complex with TRAF6| MAP3K7 and TAB1| and it thus serves as an adaptor that links MAP3K7 and TRAF6

Mutations in this gene have been found in individuals with autosomal dominant mental retardation

Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy

CD327 Polyclonal Antibody, 50ul Peptide Synthesis Different mutations in the mouseThis gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin like lectin) family of proteins. The encoded transmembrane receptor binds sialyl TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.

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