IRS-1 Polyclonal Antibody, 50ul[BT-AP04649] Protein Modification This proto-oncogene| highly-expressed in a

This proto-oncogene| highly-expressed in a variety of tumor cell lines| belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes

It may be involved in cellular excitability of restricted neurons in the central nervous system

Among its related pathways are Metabolism and Alzheimers disease

In human cardiac tissue| this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation

IRS-1 Polyclonal Antibody, 50ul[BT-AP04649] Protein Modification This proto-oncogene| highly-expressed in aIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.