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IRS-1(phospho Ser639) Polyclonal Antibody, 100ul Mechanical Pipette a Ras-responsive E3 ubiquitin ligase

SKU: 96511911245

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IRS-1(phospho Ser639) Polyclonal Antibody, 100ul Mechanical Pipette a Ras-responsive E3 ubiquitin ligaseThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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Description

a Ras-responsive E3 ubiquitin ligase

The CARD domains of both proteins have been shown to specifically interact with BCL10| a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation

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An important paralog of this gene is TXNDC12

IRS-1(phospho Ser639) Polyclonal Antibody, 100ul Mechanical Pipette a Ras-responsive E3 ubiquitin ligaseThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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