PDGF-B Polyclonal Antibody, 100ul RNA Tools Binds to the DEATH domain

Binds to the DEATH domain of p75NTR/NGFR

Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor

The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells

mutations and small deletions in ELOVL4 are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD)

PDGF-B Polyclonal Antibody, 100ul RNA Tools Binds to the DEATH domainPDGFB (platelet derived growth factor subunit B) encodes a member of the protein family comprised of both platelet derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet derived growth factor subunit A. These proteins bind and activate PDGF