Phospho-Bad (S134) Polyclonal Antibody, 50ul Sealing Film This gene is located within

This gene is located within the first intron of the ZC3H11A gene

a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination

Cleaves preferentially Lys-6 and Lys-63-linked ubiquitin chains

acute myeloid leukemia and malignant lymphomas

Phospho-Bad (S134) Polyclonal Antibody, 50ul Sealing Film This gene is located withinThe protein encoded by BAD (BCL2 associated agonist of cell death) is a member of the BCL 2 family. BCL 2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL xL and BCL 2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein