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BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates However| this gene product contains

SKU: 97294874047

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BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates However| this gene product containsBNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The encoded protein interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.

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Description

However| this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus| and a transposase domain at the C-terminus| suggesting that it may belong to the family of DNA-mediated transposons in human

This gene may influence triglyceride levels| and may be involved Type 2 diabetes| as well as several types of cancer

their beta chains are unique and confer biological specificity

The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line

BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates However| this gene product containsBNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The encoded protein interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.

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