MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Probable substrate-specific adapter of an

Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP

Inhibin beta C chain is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes

MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Probable substrate-specific adapter of anMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.