PI 3-kinase p85 Alpha/Gamma Polyclonal Antibody, 50ul Thermo Mix Mutations in this gene are

Mutations in this gene are associated with acute myeloid leukemia

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain

The gene product also affects fibroblast growth factor signaling

This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype

PI 3-kinase p85 Alpha/Gamma Polyclonal Antibody, 50ul Thermo Mix Mutations in this gene arePhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1