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Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis Also exhibits low-fidelity DNA synthesis

SKU: 97824410912

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Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis Also exhibits low-fidelity DNA synthesisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

Also exhibits low-fidelity DNA synthesis

Heme oxygenase occurs as 2 isozymes

suggested it might play a role in the regulation of transcription

May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites)

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis Also exhibits low-fidelity DNA synthesisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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