ERLN2 Rabbit Polyclonal Antibody, 100ul Cell Senescence The T-box family members share
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ERLN2 Rabbit Polyclonal Antibody, 100ul Cell Senescence The T-box family members shareThis gene encodes a member of the SPFH domain containing family of lipid raft associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1 4 5 trisphosphate (IP3) signaling by mediating ER associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia 18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms
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