LIRB3 Polyclonal Antibody, 20ul Bottles Mutations in this gene result

Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism

An important paralog of this gene is WHAMM

This gene encodes a protein that functions as an E3 ubiquitin-protein ligase

This protein forms a trimeric complex with cyclin H and MAT2

LIRB3 Polyclonal Antibody, 20ul Bottles Mutations in this gene resultLILRB3 is a member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. 4. Leukocyte Immunoglobulin Like Receptor B3 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine based inhibitory motifs (ITIMs). The receptor is expressed on immune cells