NS-1619 Size:Solid 10 mg Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CO)=C(Cl)N=C2CCCC)C=1[2H]

Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CO)=C(Cl)N=C2CCCC)C=1[2H]

InChiKey: QRDFCYMUXHUTCS-UHFFFAOYSA-N

Targeting transforming growth factor-beta signaling in liver metastasis of colon cancer

Su-11274 exhibits a selective inhibition pattern toward different receptor mutated variants

NS-1619 Size:Solid 10 mg Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CO)=C(Cl)N=C2CCCC)C=1[2H]NS1619 is a Bkca opener or large conductance Ca2+ activated potassium (BKCa, KCa1. 1) channel activator. NS1619 pretreatment protects against shock induced vascular hyporeactivity through PDZ Rho GEF RhoA Rho kinase pathway in rats. NS1619 modulates calcium homeostasis in muscle cells by inhibiting SERCA. NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle. Product information CAS Number: 153587 01 0 Molecular Weight: